What arthritis actually is
In a prior video, I discussed how osteoarthritis is largely not a wear-and-tear condition as many orthopedic surgeons claim.
Osteoarthritis is a disease, a low grade, chronic inflammatory state throughout your body. When you suffer an injury, your body makes and releases proteins called cytokines that go to the site of injury. Those cytokines can be either pro-inflammatory or anti-inflammatory cells. Pro-inflammatory cytokines – the damaging ones – include interleukin-1β, tumor necrosis factor-α, interleukin-6. When there is an abundance of pro-inflammatory cytokines, they cause tissue damage in whatever part of the body that is, like the knee or hip.
If you’re out of balance, in a chronic inflammatory state – poor diet, chronic stress, disease processes that affect your immune system – you develop a situation where those pro-inflammatory cytokines recruit degradative enzymes, like metallomatrix protease, or MMP. MMP degrades articular cartilage, creating debris of damaged cells and protein, stimulating an immune response to fight it, leading to more pro-inflammatory cytokines and more degradative enzymes, and now you're in an ongoing cycle of joint destruction.
This post is meant for educational and informational purposes only and should not be considered medical advice.
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