Introduction to Chemical Biology
In this lecture, Dr. Pol Hernández-Lladó (University of Oxford) gives us an introduction to Chemical Biology. This episode is hosted by Dr. Xingfeng Bai.
References (in order of appearance):
Nat. Chem. Biol. 2010, 6, 847-854.
For a review on the early stages of the drug discovery process see: Br. J. Pharmacol., 2011, 162, 1239-1249.
Br. J. Pharmacol., 2011, 162, 1239-1249.
Curr. Res. Pharmacol. Drug Discov. 2023, 5, 100164.
Sci. Rep. 2016, 27190; ACS Omega 2020, 5, 1, 10–18.
Proc. Natl. Acad. Sci. USA 2002, 6:99, 10335-40.
For a review see: ACS Pharmacol. Transl. Sci. 2021, 4, 1265-1279.
J. Med. Chem. 2016, 59, 2163-2178.
For a review see: ACS Pharmacol. Transl. Sci. 2021, 4, 1265-1279.
Drug. Disc. Today 2020, 25, 1998-2005.
For a review on chemical biology approaches to target identification see: Molecules, 2020, 25, 5702.
Angew. Chem. Int. Ed. 2020, 59, 2420-2428.
Further reading:
Book: H. Waldmann and P. Janning, Chemical Biology: Learning through Case Studies (Wiley-VCH, Weinheim 2009)
Perspective: A. T. Plowright, et al. Joining Forces: The Chemical Biology-Medicinal Chemistry Continuum. Cell Chem Biol. 2017, 24(9): 1058-1065
