Management and TREATMENT of neonatal HYPOGLYCEMIA
How to TREAT a low glucose in a newborn?? WHEN is a Glucose level considered LOW in babies? WHEN to treat? What if the baby has SYMPTOMS? What about feeds? What is glucose GEL? When do we give a bolus? When do we increase Dextrose concentrations? What about the GIR? When do we use other medications e.g glucagon, diazoxide, steroids, octreotide??? When do we check other hormones and labs values!
This is probably our clinically most helpful video- so find out all the answers in the video!
For the PDF summary of THIS video, links to relevant articles (+ 50 free Multiple Choice Questions/ Answers and explanations!!), AND a bunch of other stuff, subscribe to our Neonatal Nuggets Newsletter here:
https://talatalksnicu.substack.com/su...
---------------------------------------------------------------------
Please be sure to give us a like, comment about future topics, and subscribe to this channel to stay up to date on all things NICU! Also, click the notification bell after you subscribe to gain your weekly NICU knowledge as soon as it's loaded!
---------------------------------------------------------------------
Dr. Tala is a board-certified neonatologist and has worked in busy level III and IV units for the past 16 years. She has won multiple teaching awards throughout her time as a neonatologist.
----------------------------------------------------------------------
References:
Giouleka S, Gkiouleka M, Tsakiridis I, Daniilidou A, Mamopoulos A, Athanasiadis A, Dagklis T. Diagnosis and Management of Neonatal Hypoglycemia: A Comprehensive Review of Guidelines. Children (Basel). 2023 Jul 14;10(7):1220. doi: 10.3390/children10071220. PMID: 37508719; PMCID: PMC10378472
Pediatrics. 2011;127(3). doi:10.1542/peds.2010-3851
https://www.liebertpub.com/doi/full/1...
Harris DL, Weston PJ, Signal M, Chase JG, Harding JE. Dextrose gel for neonatal hypoglycaemia (the Sugar Babies Study): a randomised, double-blind, placebo-controlled trial. Lancet. 2013 Dec 21;382(9910):2077-83. doi: 10.1016/S0140-6736(13)61645-1. Epub 2013 Sep 25. PMID: 24075361.
Gupta K, Amboiram P, Balakrishnan U, C A, Abiramalatha T, Devi U. Dextrose Gel for Neonates at Risk With Asymptomatic Hypoglycemia: A Randomized Clinical Trial. Pediatrics. 2022 Jun 1;149(6):e2021050733. doi: 10.1542/peds.2021-050733. PMID: 35582897.
Harris DL, Gamble GD, Harding JE; CHYLD Study Group. Outcome at 4.5 years after dextrose gel treatment of hypoglycaemia: follow-up of the Sugar Babies randomised trial. Arch Dis Child Fetal Neonatal Ed. 2023 Mar;108(2):121-128. doi: 10.1136/archdischild-2022-324148. Epub 2022 Aug 8. PMID: 35940872; PMCID: PMC9905356.
St Clair SL, Harding JE, O'Sullivan JM, Gamble GD, Alsweiler JM, Vatanen T; hPOD Study Group. Effect of prophylactic dextrose gel on the neonatal gut microbiome. Arch Dis Child Fetal Neonatal Ed. 2022 Sep;107(5):501-507. doi: 10.1136/archdischild-2021-322757. Epub 2021 Dec 2. PMID: 34857640; PMCID: PMC9160211
https://www.med.unc.edu/pediatrics/cc...
Vanhatalo T, Tammela O. Glucose infusions into peripheral veins in the management of neonatal hypoglycemia--20% instead of 15%? Acta Paediatr. 2010 Mar;99(3):350-3. doi: 10.1111/j.1651-2227.2009.01237.x. Epub 2009 Apr 14. PMID: 19397539.
Sweet CB, Grayson S, Polak M. Management strategies for neonatal hypoglycemia. J Pediatr Pharmacol Ther. 2013 Jul;18(3):199-208. doi: 10.5863/1551-6776-18.3.199. PMID: 24052783; PMCID: PMC3775554
Adamkin DH. Neonatal hypoglycemia. Semin Fetal Neonatal Med. 2017 Feb;22(1):36-41. doi: 10.1016/j.siny.2016.08.007. Epub 2016 Sep 4. PMID: 27605513
Watch this too: • The CHYLD Study
----------------------------------------------------------------------------
**TIMESTAMPS**
00:32 Definition of hypoglycemia
09:45 Management of hypoglycemia
----------------------------------------------------------------------------
*Disclaimer*: This video is intended for educational purposes only and while we strive to give the most accurate information, errors may occur. Subsequently, this video should not be a replacement for medical advice.
