Here is a guide on Altar of Hope upgrades and what to focus on during early runs. There are many upgrades available but not everyone is as important at the start. Imo this is how Altar of Hope should be upgraded.
Item list of helpful things from the end of video to get in the game through Working Fields early:
Healing Salve
Triage Kit
Adrenaline
Congealed Slime
Windchime
Pot and Still
Whiskey Flask
Whittling Tools
The Blood
Glimmer of Hope
Tinned Delicacies
The Wine
Bulbous Venom Gland
Mineral Spring Water
Chitinous Appendage
Restorative Herbs
Milk-soaked Linen
Pipeweed
Nightshade Concoction
Meditative Totem
Leeches
Medical Equipment
Leaf Suspension
Laudanum
Invigorating Toxicant
Impressive Incisors
Mixing Kit
Calming Incense
Candles & Chocolate
Book of Bawdy Tales
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