In Python, a tuple is an ordered, immutable sequence of values that can be of any data type. Tuples are similar to lists, but they cannot be modified once they are created. Tuples are often used for representing collections of related data, such as the coordinates of a point or the RGB values of a color. They can be easily created using parentheses or the tuple() function, and can be accessed using indexing or slicing. Tuples are a fundamental data structure in Python and are widely used in data processing and scientific computing.