A Highly Efficient Tumor-Targeting Nanoprobe with a Novel Cell Membrane Permeability Mechanism
Graphene-based tumor cell nuclear targeting fluorescent nanoprobe (GTTN) with cell membrane permeability targeting mechanism has been developed. GTTN can recognize tumor cells in a very early stage and track the tumor cells at the single cell level but do not enter into normal tissue cells. The tumor-targeting rate has been improved from less than 5% to more than 50%.
This is reported by Zhendong Lei, Lin Ding, Chenjie Yao, Fengfeng Mo, Chenchen Li, Yanan Huang, Xuelian Yin, Min Li, Jinliang Liu, Yong Zhang, Changquan Ling, and Yanli Wang in their article: https://doi.org/10.1002/adma.201807456.
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