Colloquium ICMM 26/04/2021
Dr. Lluís Montoliu
Dpto. de Biología Molecular y Celular (CNB-CSIC), Madrid
Emmanuelle Charpentier (Max-Planck-Society, Berlin, Germany) and Jennifer Doudna (University of California, Berkeley, CA, USA) were awarded the Nobel Prize in Chemistry 2020 for the development of a method for genome editing. These two researchers met in 2011 and began a single scientific collaboration that crystalized in a publication in Science in June 2012 where they proposed to use an immune defence system invented by the prokaryotes as a tool for triggering genome editing in all living organisms. Their proposal was based on years of previous basic research led by many microbiologists, notably Francis Mojica (University of Alicante) who first described the system ten years before and invented the name of CRISPR. In this webinar I will explain the reasons why these two researchers were awarded, their merits and will illustrate the impact of this disruptive technology with several examples from our own research at CNB-CSIC, where we apply the CRISPR tools to advance in our understanding of the non-coding genome and in the generation of patient-specific animal models of human rare diseases.
More related videos to Dr. Montoliu research work:
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http://wwwuser.cnb.csic.es/~montoliu/...