Centenarians do not carry fewer pathogenic mutations | Lifespan News

Опубликовано: 01 Апрель 2025
на канале: Lifespan Extension Advocacy Foundation

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▼▼ Description, sources, and more below ▼▼

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In this episode of Lifespan News:

0:00 Intro
0:14 Alpha-Ketoglutarate Extends Healthspan in Aging Mice
1:12 Microglial Cells Successfully Replaced by Transplantation
2:20 Inherited methylation patterns affect aging
3:04 Centenarians do not carry fewer pathogenic mutations
3:42 How can aging be reversed? Exploring rejuvenation from a damage‐based perspective

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Executive Producer: Keith Comito
Producer: Nicola Bagalà
Assistant Producer: Sedeer el-Showk
Video Editors: Tim Maupin, Brent Nally
Text Editor: Josh Conway

SOURCES AND FURTHER READING
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Alpha-Ketoglutarate Extends Healthspan in Aging Mice:
https://www.lifespan.io/news/alpha-ke...
https://www.cell.com/cell-metabolism/...

Microglial Cells Successfully Replaced by Transplantation:
https://www.lifespan.io/news/microgli...

Inherited methylation patterns affect aging:
https://www.eurekalert.org/pub_releas...
https://onlinelibrary.wiley.com/doi/f...

Centenarians do not carry fewer pathogenic mutations:
https://onlinelibrary.wiley.com/doi/f...

How can aging be reversed? Exploring rejuvenation from a damage‐based perspective:
https://onlinelibrary.wiley.com/doi/f...

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#Aging #Lifeextension #AlphaKetoglutarate #Lifespan #Healthspan #Centenarians #Methylation #Microglia #Rejuvenation