Open Box Science

[Lenka Dohnalova] Ｍicrobiota-derived metabolites regulate motivation for exercise

[Kenichiro Motomura] Fetal and maternal NLRP3 signaling is required for preterm labor and birth

[Jorge Galeano]Effect of the intratumoral microbiota on spatial and cellular heterogeneity in cancer

[Nuriban Valero-Pacheco] Maternal IL-33 critically regulates tissue remodeling and type 2 immune...

[María Casanova-Acebes] Tissue-resident macrophages provide a pro-tumorigenic niche to early NSCLC

[Margaret L. Axelrod] T cells specific for α-myosin drive immunotherapy-related myocarditis

[Colin YC Lee] A scRNA-seq atlas of immune cells at the CNS borders

[Christos Lisgaras] Oscillations in Alzheimer's models

[Darshan Sapkota] Neurobiological significance of alternative modes of mRNA translation in astrocyte

[Daping Yang] Nociceptor neurons direct goblet cells via a CGRP-RAMP1 axis to drive mucus production

[Lenka Dohnalova] Ｍicrobiota-derived metabolites regulate motivation for exercise

[Synphane Gibbs-Shelton] Microglia play beneficial roles in multiple experimental seizure models

[Junhong Choi] Molecular recording using precision genome editing

[Nataliya Prokhnevska] CD8+ T cell activation in cancer

[Mireia Valles-Colomer] The person-to-person transmission landscape of the gut and oral microbiomes

[Hui-Hao Lin] Gut-to-brain communication of nutritional information prioritizes courtship...

[Zoé Christenson Wick] Manipulating single-unit theta phase-locking with PhaSER: An open-source tool

[Ammar Tareen] MAVE-NN: learning genotype-phenotype maps from MAVE

[Lucia Borriello]How does the primary tumor imprint a dormancy signature in disseminated tumor cells

[Patricia Altea Manzano] PHGDH heterogeneity potentiates cancer cell dissemination and metastasis

[Niamh B. McNamara] Microglia regulate central nervous system myelin growth and integrity

[Takeshi Egawa] Durable CD4 T cell Immunity to persistent antigen by population hierarchy

[Giovanni Quinones-Valdez] Function and Regulation of Nucleotide Variants in RNA

[Achille Broggi ] Type III interferons disrupt the lung epithelial barrier upon viral recogniti

[Julia Zeitlinger] Base-resolution models of transcription-factor binding reveal soft motif syntax

[John Liao] Neurophysiological basis of stress-induced aversive memory in the nematode C. elegans

[Kathy Ayasoufi] Brain resident memory T cells rapidly expand and initiate neuroinflammatory...

[Open Box Science] 2022 Symposium in Science Communication

[Priya Devarajan] How are lung cytotoxic CD4 effectors generated during infection?

[Aymeric Silvin] Dual ontogeny of disease associated microglia and disease inflammatory...

[Anthony Umpierre] Microglial calcium signaling is attuned to neuronal activity in awake mice

[Ángel Álvarez-Prado] Immunogenomic analysis of human brain metastases

[Sarah Maritan and Miranda Yu] Spatial immune landscapes of primary and metastatic brain tumours

[Noa Rachmian] Identification of senescent, TREM2-expressing microglia in aging & AD mouse brain

[Alon Millet] An exhausted-like microglial population accumulates in aged & APOE4 genotype AD brains

[Nadezhda Terekhanova] Epigenetic regulation during cancer transitions across 11 tumour types

[Leyuan Ma] Vaccine-boosted car t crosstalk with host immunity to reject tumors with antigen...

[ Alex Chen ] The aged tumor microenvironment limits T cell control of cancer

[Wei Su] CD8 T cells: friend or foe in neurodegeneration

[Fran Martínez Jiménez] Unraveling the immunogenics determinants of metastasis across human cancers

[Zeribe Nwosu] Uridine-derived ribose fuels glucose-restricted pancreatic cancer

[Jesus Corria-Osorio] Orthogonal cytokine engineering enables novel synthetic effector states...

[Nicoletta Caronni] IL1beta+ macrophages fuel pathogenic inflammation in pancreatic cancer

[Olga Zimmermannova] Restoring tumor immunogenicity with dendritic cell reprogramming

[Nathaniel D. Bachtel] Immune sensing of food allergens promotes avoidance behavior

[Meghan Laturney] How the neuroendocrine circuit that regulates sugar feeding in mated females

[Khalid El Bairi] A Focus on Plagiarism and Predatory Publishing

[Jimmy Zhang] ML Identify Predictive Features of Patient Mortality across Dementia

What is Polygenic Risk Score? A Primer

OBS Immunology: Immune Engineering

[Piotr Konieczny] Metabolic coordination between skin epithelium and type 17 immunity sustains...